Interrogating genomes through next generation sequencing
September 22, 2011
2:30 p.m.
Scott Dindot
Abstract
Next-generation sequencing (NGS) has revolutionized the field of genomics. NGS methods such as massively parallel sequencing and pyrosequencing have made possible the interrogation of the whole-genomes for the purpose of identifying disease causing mutations; identifying and characterizing genetic variants underlying phenotypic variation; and for performing analyses of genetic variation within and among populations. I will discuss current applications of NGS technology, computational requirements and limitations, and the future of NGS technology in biomedical and veterinary research.